What is Triple-Negative Breast Cancer?
What are Triple-Negative Breast Cancer’s Survival and Recurrence Rates?
Triple-negative breast cancer refers to cancer cells that do not produce a lot of human epidermal growth factor receptor 2 and do not contain oestrogen or progesterone receptors (HER2). Doctors will perform tests to look for these receptors and protein synthesis when determining the sort of cancer that is present. A person has triple negative breast cancer if all three tests are negative.
Breast cancer can also take the following forms:
- positive for oestrogen receptors
- positive for progesterone receptors
- the HER2 receptor is active
Doctors can use hormone therapy to specifically target cancer if cancer cells test positive for these receptors.
But there are no targeted treatments for triple-negative breast cancer. Additionally, it is more likely to spread and return than other forms of breast cancer.
Current explanations for the origins of both hormone-receptor-positive and triple-negative breast tumours are different. A woman’s reproductive traits, such as the age at which she gave birth to her first child, have been associated to certain breast cancers that develop in response to hormone exposure. This association does not appear to exist for triple-negative breast cancer.
- Obesity and inactivity
What Causes Triple Negative Breast Cancer?
Many patients are curious as to the origin of triple-negative breast cancer. This question is frequently posed by breast cancer specialists, but there are currently no definitive solutions.
While there are no targeted treatments for triple-negative breast cancer, cancer treatment in India offers advanced options, including chemotherapy, radiation therapy, surgery, targeted therapy, and immunotherapy. These treatments can help improve survival rates and reduce the likelihood of recurrence.
More knowledge regarding the causes of triple negative breast cancer in particular and breast cancer in general is emerging as research advances.
In contrast to other forms of breast cancer, triple negative breast cancer is distinguished by the absence of oestrogen, progesterone, or HER-2/neu hormone receptors in the cancer cells. When these receptors are present and in contact with the appropriate hormones, they can promote the growth of the malignancy. As a result, hormone-based therapies like tamoxifen and Herceptin—which can be helpful for treating hormone-receptor-positive cancers—do not help people with triple-negative breast cancer.
A person may have a little, hard bump on or around their breast, similar to other types of breast cancer. In other situations, a normal breast scan may spot a problem location. When a growth is found, the doctor will take tissue samples for analysis. The outcomes of these tests will identify the breast cancer kind. Triple-negative breast cancer is the term used to describe a patient whose cancer tests negative for the HER2, progesterone, and oestrogen receptors. The results of the biopsy and any subsequent scans will be used by the doctor to determine the cancer’s stage. The size of the tumour and the extent of the cancer’s dissemination, if any, are used to determine the stage.Breast Cancer , Cancer Treatment