Five Breast Cancer Treatments apart from Chemotherapy
Treatment for breast cancer isn’t quite tailor-made. It is, nevertheless, more individualised than ever before, specially when you are doing it from the experts of cancer treatment in India.
Treatment options for breast cancer can differ significantly from one woman to another depending on the genetic and cellular characteristics as well as her age, health, and medical history (including inherited genetic abnormalities that can contribute to breast cancer), how rapidly it’s growing, and how far it’s spread.
Chemotherapy may no longer be necessary, thanks to new breast cancer medicines that target particular hormones and proteins involved in the disease’s growth. In fact, one can get the best cancer treatment in India without ever taking any chemo sessions,
Whether experimental or not, every woman should weigh the benefits and drawbacks of any treatment her oncology team advises.
Let’s have a look –
Surgery is a common treatment for breast cancer. The type of surgery has varied over the years. Breast-conserving surgery, often known as a lumpectomy, is currently performed on a large number of women. The tumour and some surrounding tissue are removed, but as much healthy breast tissue as possible is preserved.
Mastectomy (whole breast removal) is a less common procedure. Partial mastectomy, which entails removing a major portion of the breast, is one variation of this operation (larger than lumpectomy). Bilateral or double mastectomy refers to the removal of both breasts. The skin is preserved for breast reconstruction after a skin-sparing mastectomy.
An axillary lymph node dissection is an alternative procedure. Multiple lymph nodes under the arm are removed during this procedure.
These high-intensity therapies break cancer cells’ DNA, making it impossible for renegade cells to replicate or repair themselves. It’s frequently used after a lumpectomy and, on rare occasions, after a mastectomy, as well as in individuals with cancer that has progressed to the lymph nodes or adjacent tissue. It may be used to reduce a big tumour prior to surgery in rare situations.
The most common method of treatment is external beam radiation, which is delivered by a machine outside the body. What distinguishes it is the manner in which it is conveyed.
Intraoperative radiation therapy is a relatively new option. During surgery, the patient receives a single dosage of radiation to the area where the cancer was found. Another method, known as brachytherapy, is placing a catheter or balloon into the location where the tumour was removed and delivering radiation to the area.
Hormone therapy is given to women with certain sorts of malignancies to delay or stop tumour growth. Hormone-sensitive cancers have “receptors” that bind to oestrogen, progesterone, or both oestrogen and progesterone. A tissue sample will be extracted and examined to see if yours is oestrogen receptor-positive (ER-positive) and/or progesterone receptor-positive (PR-positive). Tamoxifen is a hormone treatment that is frequently administered. It prevents oestrogen from attaching to oestrogen receptors, which is how it works. Another type of hormone therapy is aromatase inhibitors. Because these medications inhibit oestrogen production, they are typically prescribed to women who have already reached menopause.
CDK4 and CDK6
Cyclin-dependent kinases (CDK) are proteins in the body that help cancer cells to divide and grow. Inhibitors of CDK4 and CDK6 are designed to stop this process. When compared to anti-hormone therapy alone, they extend the time until the disease advances.
PARP (poly ADP-ribose polymerase) is a cellular enzyme that aids in the repair of damaged DNA. Blocking PARP in women with a mutant BRCA gene (BRCA1 or BRCA2) can thwart cancer-cell repair and speed the demise of these rogue cells, according to research.
Certain patients with a hereditary BRCA mutation whose breast cancer has progressed to other parts of the body may benefit from olaparib (Lynparza). It’s also linked to malignancies of the blood and bone marrow.Cancer Treatment
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